Progression analysis – Optotech | Clinical & Technical Resources

Glaucoma Lifetime Progression & Impairment Analyzer

Patient Age (Years)

Current MD (dB)

MD RoC (dB/year)

sLV (dB)

cpRNFL Thickness (µm)

cpRNFL RoC (µm/year)

GCL++ Thickness (µm)

GCL++ RoC (µm/year)

Central scotoma present (within 15°)

Evidence-Based References:

The Structural Floor: Miki et al. (2014) – *Ophthalmology*. Rates of cpRNFL thinning reach a baseline floor of ~45-50µm in advanced disease.
Functional Impairment: Saunders et al. (2014) – *IOVS*. MD of -20 dB correlates with legal blindness and significant loss of independent mobility.
Central Scotoma Impact: Hood et al. (2013) – *PRER*. Central 10° scotomas correlate with severe QoL impairment regardless of global MD.
Competing Mortality: Actuarial Life Expectancy derived from WHO Statistical Information System (WHOSIS) global averages.